Nutrition Diagnostics - The Dangers of Methylated B Vitamins and Mercury

The Dangers of Methylated B Vitamins and Mercury


Why is vitamin B-12 as a supplement or additive dangerous? Many Universities have published articles on the ability of Vitamin B-12 to convert mercury vapor into the much more deadly "Methyl mercury". Methyl mercury knows no barriers, and creates far more havoc than other mercury chemicals, because of its ability to travel anywhere in the body without inhibitions. Sometimes the effects of high doses of Vitamin B-12 (over 50 micrograms) take months to correct.

There are several B12 supplements available to the public. However, not every kind is useful, active or even safe for humans. Adenosylcobalamin and methylcobalamin remain two of the most bio-availably active forms. However, there are issues with supplementation that must be addressed. Deficiencies can’t always be solved by replacing lost nutrients with supplements. This is explained below:

Vitamin B12 refers to a collection of corroid compounds which act on certain enzymes in the body. Its functionality depends on other vitamins; namely B6 and folic acid. These allow B12 to be absorbed and carry out important chemical reactions. These largely include the production of s-adenosyl-methionine (a mood enhancer), methionine and cysteine, (critical amino acids for the methylation of homocysteine and other biological pathways).

Most vegetarians are deficient in many trace minerals. Whether or not plant foods contain any nutrients is not the topic in question. They may well eat foods that contain a diverse range of minerals. However:

1)      There is NOT ENOUGH of these in plant foods to solely sustain human health

2)      Vital deficiencies such as PROTEIN, IRON AND B12 limit the efficacy and bio-availability of other nutrients, regardless of supplementation and/or food combining

3)      Any short-term advantages from micro-supplementation are overridden by the adverse effects of a meatless diet i.e. glucose and insulin problems, low total protein, low cholesterol, etc.

Despite their best efforts, vegetarians don’t have an ideal mineral status. B12 relies on certain mineral substrates to lend its positive functions. These deficiencies can influence its methylating abilities. Therefore, B12 supplementation in this scenario risks potentially serious adverse events.

         B12 given in isolation can cause methylating disturbances which prevent the transformation of homocysteine. The conversion to its harmless amino acid form depends on B12’s interaction with other key minerals. Homocysteine toxicity can arise, causing cardiovascular threats, oxidative damage and aging.


         B12’s role as a methyl donor means that toxins are at risk of being stimulated. Dangerous heavy metals such as mercury are often inadvertently methylated by giving B12 on its own in high doses. This can exacerbate existing toxicities and enhance their detrimental effects.


The important point to note is that B12 supplements will not work effectively in the context of a poor diet. Continued supplementation without addressing overall nutrient status can produce the above outcomes. For this reason, individual B12 supplements should only be given with great care and consideration.


Intra-muscular B12 injections are regularly administered in much depleted patients. However, this bears the same negative effect as supplementing individually. B12 injections are known to methylate mercury, a particularly lethal neurotoxin. All humans are exposed to heavy metals and toxins throughout their lifetime. The effects of mercury can be serious and are ominously unpredictable. Additionally, patients can suffer from side effects due to the preservatives in the solution. These can range from minor complaints to serious complications. There is a very narrow window for the administration of intra-muscular B12. Individuals suffering from certain optic, hepatic and renal diseases can never have the injections. Anyone receiving treatment for bone marrow disorders cannot accept them. And of course anyone afflicted with cobalt allergies is not eligible. The form of B12 used is often one of several undesirable types. The methylation of toxins as well as the presence of artificial preservatives offers a toxic and altogether unappealing alternative.